Burke, professor of nursing and epidemiology at the University of Pittsburgh School of Nursing and Graduate School of Public Health, received her M.N. from the UCLA School of Nursing with a cardiovascular specialty, then completed her Ph.D. in nursing and M.P.H. in epidemiology at the University of Pittsburgh, followed by a two-year postdoctoral fellowship in cardiovascular behavioral medicine at the same institution, where she has been a member of the faculty since 1999. Starting with a National Research Service Award as a doctoral student, Burke has had continuous National Institutes of Health funding to support her research program, which has included a series of clinical trials focused on behavioral strategies to improve compliance to treatment regimens targeting cardiovascular disease risk reduction and long-term weight loss. She has incorporated the use of technology to validate self-report measures, and was the first to document actual patterns of self-monitoring among participants in behavioral treatment for weight-loss studies. An active mentor of junior faculty members and students, Burke has also maintained leadership positions in the American Heart Association and the Society of Behavior Medicine.